Test Your Knowledge: Kidney Transplantation and the Human Immunodeficiency Virus (HIV)

A recent article by Chandran et al published in the American Journal of Kidney Diseases describes a case of recurrent HIV-associated immune complex disease with lupus-like features following kidney transplantation. The following questions will test your knowledge on kidney transplantation and HIV-related kidney disease: 1. Finding the appropriate dose of calcineurin inhibitors (CNI) in a […]

Test Your Knowledge: Transplant Glomerulopathy

Frequent double contours along the glomerular capillary loops (arrows). Methenamine silver; original magnification, ×400. Image courtesy of Dr. Tibor Nadasdy.

There is recent interest in understanding the cause of late allograft failure in kidney transplant recipients. One pathologic marker of poor allograft outcome is transplant glomerulopathy. A recent article by Husain and Sis published in the American Journal of Kidney Diseases reviews transplant glomerulopathy. The following questions will test your knowledge on transplant glomerulopathy: A […]

Test Your Knowledge: Central Vein Stenosis

Central vein stenosis (CVS) is commonly seen in patients on hemodialysis. A recent review by Dr. Anil Agarwal in American Journal of Kidney Diseases discusses the causes and prevention of this entity. The following questions based on the article will test your knowledge on CVS. 1. The most common cause of CVS is: A. Idiopathic […]

Test Your Knowledge: Hypomagnesemia

In a teaching case recently published in the American Journal of Kidney Diseases, Dimke et al present a case of hypomagnesemia and hypokalemia. The following questions will test your knowledge on renal magnesium handling and the evaluation of hypomagnesemia. 1. Which nephron segment reabsorbs the majority of filtered magnesium? A. Proximal tubule B. Thick ascending […]

Test Your Knowledge: Renal Artery In-Stent Stenosis

Controversy exists in the management of renal artery stenosis (RAS) after recent trials have shown conflicting results with regard to angioplasty. A recent article by Boateng et al in the American Journal of Kidney Diseases discusses the prevalence, risk factors, and treatment of in-stent stenosis in the setting of RAS. The following questions will test […]

Test Your Knowledge: Hepatitis C and the Kidney

A: PAS stain of a representative glomerulus; original magnification, x600. B: Glomerular staining for IgG by direct immunofluorescence; original magnification, x400 (similar staining was noted for IgM). C: High magnification EM image taken of a glomerular deposit; original magnification, x80,000. Images courtesy of Dr Tibor Nadasdy.

In a recent article in the American Journal of Kidney Diseases, Fabrizi et al review hepatitis C virus and kidney disease with focus on cryoglobulinemia. The following questions will test your knowledge on hepatitis C virus–associated kidney diseases: 1. A 41-year-old woman with recent diagnosis of hepatitis C infection was found to have an elevated […]

Test Your Knowledge: Central Diabetes Insipidus

In the December issue of the American Journal of Kidney Diseases, Dy et al discuss an association of central diabetes insipidus with acute myelogenous leukemia (AML). Central diabetes insipidus is a condition that may be due to many other causes. The following questions will test your knowledge on central diabetes insipidus. 1. Which of the […]

Test Your Knowledge: Phosphate Metabolism

Our understanding of phosphate regulation is changing as newer mediators such as fibroblast growth factor 23 (FGF-23) emerge. Parathyroid hormone (PTH) and phosphate balance is an integral part of chronic disease kidney care. In a teaching case recently published in the American Journal of Kidney Diseases, Leaf and Wolf discuss a physiologic-based approach to the […]

Test Your Knowledge: Hypokalemia

In the September issue of the American Journal of Kidney Diseases, Asmar et al summarize a physiologic approach to the treatment of hypokalemia. The following questions will test your knowledge of hypokalemia. 1. Liddle syndrome is characterized by each of the following except: A. Chronic hypokalemia B. Hypotension C. Suppressed serum aldosterone D. Suppressed plasma renin activity […]

Test Your Knowledge: The Rise of C3 Glomerulopathies

EM, uranyl acetate - lead citrate; original magnification, x8000. Image courtesy of Dr. Tibor Nadasdy.

In a recent article published in the American Journal of Kidney Diseases, Sandhu et al describe a case of C3 glomerulopathy masquerading as acute post-infectious glomerulonephritis. Test your knowledge on this novel entity of C3 glomerulopathy. 1. A 60-year-old man with no significant past medical history presents with increasing fatigue and worsening lower extremity edema […]

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