SCM14: Let’s Bind With Velphoro

SCM14 logo

Dr. Stuart Sprague (SS) from the North Shore University Health System and University of Chicago Pritzker School of Medicine discusses his abstract for the National Kidney Foundation’s 2014 Spring Clinical Meetings (SCM14), Concomitant Intravenous Iron Use Drives Changes in Iron Indices in a Phase 3 Study of PA21, with Dr. Kenar Jhaveri (eAJKD), eAJKD Editor. […]

Hypertension, Proteinuria, and Phosphate: A Bad Combination!

Cozzolino et al Fig 1

Invited commentary by Dr. Edgar Lerma In recent years, the epidemic of chronic kidney disease (CKD) and its association with increased cardiovascular morbidity and mortality has become clear. As nephrologists, we are responsible for instituting measure to delay progression of CKD, including control of hypertension and diabetes, and avoidance of nephrotoxic agents. Several studies have […]

Test Your Knowledge: Phosphate Metabolism

Our understanding of phosphate regulation is changing as newer mediators such as fibroblast growth factor 23 (FGF-23) emerge. Parathyroid hormone (PTH) and phosphate balance is an integral part of chronic disease kidney care. In a teaching case recently published in the American Journal of Kidney Diseases, Leaf and Wolf discuss a physiologic-based approach to the […]

Sex and Estrogen Therapy and Their Influence on FGF-23 and Phosphate Levels


It is known that estrogen can mitigate menopause-associated urine phosphate retention. A recent cross-sectional study of ambulatory individuals with prevalent cardiovascular disease published in this issue of AJKD explores the role of sex and use of estrogen in phosphate and FGF-23 levels. The author, Dr. Joachim H. Ix (JI) from University of California San Diego, […]


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