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NephMadness is not decided by popular vote (see Mommy where do winners come from), but we do have the data on the popular votes. If you go to the statistics page at Tourneytopia you can see the top vote-getters but not how the voting went round by round. We have crunched the numbers for you. Here is the popular vote from round one (the actual winners of each match-up are in bold):

Toxin Region:

1 Aristolochic Acid: 180
8 Hemoperfusion: 80

3 Toxic Metals: 111
6 Fomepizole: 149

5 Chelation Therapy: 128
4 Glycyrrhizic Acid: 132

7 Osmolar Gap: 182
2 DSHEA 1994: 78

The popular vote predicted all of the eventual winners except DSHEA 1994, which got trounced.

Hypertension Region

1 ACEi ARBs combo: 173
8 Renal Artery Tx: 87

3 Systolic BP: 199
6 Diastolic BP: 61

5 Chlorthalidone: 195
4 HCTZ: 65

7 KDIGO BP in CKD: 125
2 JNC8: 135

Renal artery therapy lost in a landslide yet moved on in the bracket.

Renal Replacement Therapy Region

1 Convective Clearance: 157
8 Diffusive Clearance: 103

3 Buttonhole Technique: 54
6 Residual Renal Function: 206

5 Fistula First: 141
4 Acute PD: 119

7 DreamRCT: AKI: 124
2 DreamRCT: ESRD: 136

Convective clearance has captured the imagination of the crowd but was denied in our game, same with Fistula First.

Regeneration Region

1 Parietal Epithelial: 179
8 Renin Lineage: 90

3 Renal Pericytes: 177
6 EMT: 83

5 Tubules Self-Duplication: 87
4 Resident Stem Cells: 173

7 Hypertrophy: 70
2 Bioartificial Kidney: 190

One of only two regions where the wisdom of the crowd matched the whim of the Game makers.

Acute Kidney Injury Region

1 Contrast Nephropathy: 197
8 RIPC: 63

3 U/A and Indices: 127
6 AKI Biomarkers: 133

5 Balanced Solutions: 125
4 Normal Saline: 135

7 KDOQI AKI: 71
2 KDIGO AKI: 189

Upsets all over the place. AKI was where brackets came to die. The only agreement with the Game makers was contrast nephropathy. Interesting.

Electrolyte Region

1 Hypertonic Saline: 162
8 Vaptans: 98

3 Serum Anion Gap: 203
6 Urine Anion Gap: 57

5 ZS-9: 121
4 Kayexalate: 139

7 Bicarb in CKD: 196
2 Bicarb in Acute MA:64

The only disagreement was in the potassium binders.

Kidney Stone Region

1 Surgical Acute Care: 118
8 Medical Acute Care: 142

3 CT Scan: 160
6 XO Inhibitors: 100

5 Dr. Charlie Pak: 119
4 Dr. Fred Coe: 141

7 Bariatric Surgery: 122
2 Oxalobacter: 138

Another perfect match of crowd and Game makers.

Biologics Region

1 Rituximab: 214
8 Bortezomib: 46

3 Belimumab: 88
6 Belatacept: 172

5 Eculizumab: 212
4 Soluble CR1: 48

7 ACTHAR Gel: 96
2 Abatacept: 164

Crowd did pretty good here, they only missed ACTHAR Gel, to which we have to say, there’s a whole lotta people with membranous nephropathy.

Click here to view all eAJKD content about NephMadness 2014!