Barbiturate Poisoning and the Role of the Nephrologist


Extracorporeal treatments represent a life-saving intervention for many poisonings. In some instances such as salicylate toxicity, lithium toxicity, and poisoning with volatile alcohols, the indications for initiation of extracorporeal treatment are fairly straightforward. For less common poisons, knowledge about protein binding, volume of distribution, molecular weight, and prior reports of treatment are essential. Although no […]

Vascular Access in High Risk PD Patients?

Pulliam et al AJKD Fig 2

With the recent changes in the healthcare system brought about by the current economic climate paving the way for “prospective payment bundling,” there has been growing interest in home therapies (e.g., peritoneal dialysis, home hemodialysis) along with its cost advantages. In a recent retrospective study published in AJKD, Pulliam et al investigated the early outcomes […]

Peritonitis: Where Do We Stand?


In their article “Peritoneal Dialysis–Related Peritonitis: Towards Improving Evidence, Practices, and Outcomes,” Cho and Johnson discuss the epidemiology, risk factors, diagnosis, and treatment of peritonitis. Peritoneal dialysis (PD) currently makes up approximately 11% of the global ESRD population, and peritonitis directly contributes to approximately 20% of PD technique failures and 2-6% of deaths. As PD […]

AKI: What Do the Nephrologists Think?

Dr. Sarah Faubel

Acute kidney injury occurs in about 10% of hospitalized patients, but what is less known is the amount of effort AKI consumes in a nephrologist’s day? Does hospital AKI spill over to outpatient follow-up? Do nephrologists use current guidelines in prescribing dialysis for AKI? All of these questions were unknown when the ASN’s AKI Advisory […]

Does a Fasting Phosphorus Predict Mortality?

Chang & Grams AJKD Fig 1

Observational studies have demonstrated an association between serum phosphorus level and mortality in healthy individuals and in patients with chronic kidney disease (CKD) or end-stage renal disease (ESRD). Serum phosphorus levels exhibit high variability in relation to food intake. In most of these observational studies, phosphorus levels are usually measured randomly, without any mention of […]

Three Times a Week Dialysis: Is There Evidence for This Dogma?


In an article recently published in AJKD, Kalantar-Zadeh and colleagues present a unique perspective on initiating hemodialysis by questioning the dogma of thrice-weekly treatments. The authors provide the history behind thrice-weekly dialysis treatments, and discuss some of the potential adverse effects of dialysis stemming from the loss of residual kidney function (RKF). Their primary argument […]

GFR Estimating Equations in Solid Organ Transplants: Where Do We Stand?

Dr Kamran Shaffi

In a recent study published in AJKD, Shaffi et al evaluated the efficacy of different GFR estimating equations in a large cohort of solid organ transplant recipients. First author Dr. Kamran Shaffi (KS) discusses the study with Dr. Vinay Nair (eAJKD), eAJKD Advisory Board member. eAJKD: What inspired the idea of this study? KS: Physicians […]

Page the Renal fellow, please!


Much has been made about the decline of physicians entering a career in nephrology over the last decade. To be fair, this is a predicament with multiple factors at play. One such factor is work-life balance. It has recently been shown that ~50% of nephrology fellows show some degree of dissatisfaction in their career choice secondary […]

2 AM. Pager beeps… Nephrology Consult please.


2 AM. Pager beeps… Nephrology Consult please. “My patient has a serum potassium of 6.4 mEq/L. Can you please assist with his management?” “What is he admitted for? Is he hemodynamically stable? Does he have EKG changes? What is his kidney function?” “Cellulitis of the leg. Yes, he is stable. No EKG changes. Kidney function […]

Insight into Patients’ & Caregivers’ Perspectives on Conservative Management in End of Life Care

Dr. Katherine Cheung

Patients with end-stage kidney disease often experience clinical and psychological set backs that negatively impact quality of life and survival. Growing data suggest a role for conservative (non-dialytic) management for patients with advanced comorbidities. Conservative care is a refocusing of management on quality of life over quantity of life. Tong and colleagues conducted a systematic […]


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