Commentary
Commentaries are short perspectives by experts on AJKD articles or nephrology news.
Many different definitions of contrast-induced nephropathy (CIN) have appeared in the literature since it was first reported in 1954. It is commonly defined as an acute decline in kidney function following the administration of intravenous iodinated
[read more...]Understanding the pathophysiologic mechanism(s) of thiazide-associated hyponatremia (TAH) is a coming-of-age moment for nephrologists. Sure, we all learned in medical school that thiazides can cause hyponatremia, hypercalcemia, hypokalemia, etc. but
[read more...]Tension – nephrologists live in it. The tension between trying to delay chronic kidney disease (CKD) progression whilst also preparing a patient for dialysis. Tension with administrators who are targeting metric achievement when we know that
[read more...]Acute kidney injury (AKI) is common in hospitalized patients and is associated with high morbidity and mortality, especially if requiring renal replacement therapy. Continuous renal replacement therapy (CRRT) is indicated in patients who are
[read more...]Women of reproductive age with chronic kidney disease (CKD) who desire to have children face potential complications during pregnancy. Today we will use a recent AJKD perspective, “Women’s Reproductive Health for the Nephrologist,” in addition
[read more...]Overview of Metabolic Acidosis in CKD The presence of a mildly diminished bicarbonate in advanced chronic kidney disease (CKD) is one of the more polarizing topics in nephrology. Some would argue that the impaired acid-base homeostasis will lead
[read more...]When I was a medical resident, a novel developmental therapy for the treatment of certain cancers was to medically shut off the blood supply and cause ischemia to the mass. Avastin (bevacizumab), or anti-VEGF (vascular endothelial growth factor)
[read more...]Intradialytic hypotension (IDH) is sometimes defined as a decrease in systolic BP by ≥20 mm Hg or a decrease in mean arterial pressure of 10 mm Hg associated with symptoms. There are, however, other definitions of IDH in the literature. Whereas
[read more...]In the United States, approximately 37 million people in the United States have chronic kidney disease (CKD), and in 2016, there were more than 720,000 patients with ESRD on various renal replacement therapies (hemodialysis, peritoneal dialysis, or
[read more...]Membranoproliferative glomerulonephritis (MPGN) is a pattern of glomerular injury on light microscopy that is characterized by mesangial expansion with hypercellularity, endocapillary proliferation, and double-contour formation along the glomerular
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