HCV D+/R- Kidney Transplantation in the Real-World: Is It Time?
The emergence of direct acting antiviral (DAA) therapy for hepatitis C (HCV) has arguably been one of the most exciting developments in kidney transplantation in the United [...]
Commentary
Commentaries are short perspectives by experts on AJKD articles or nephrology news.
Will You Take the Blue or Red Pill?
Calcium channel blockers (CCBs) and renin-angiotensin-system inhibitors (RASi) are two classes of antihypertensive medications frequently used as initial therapy for [...]
Could High Be Better Than Low? Targeting Phosphate in Trials
Phosphate is bad, right? As kidney function declines, phosphate excretion goes down. Serum phosphate levels rise, causing parathyroid hormone (PTH) to increase and bring [...]
A Patient Behavior Modification to Increase Fluid Intake: The PUSH Trial
With the prevalence of urinary stone disease (USD) nearly doubling over the last 15 years, there has been a concomitant rise in the impact it has on our healthcare system. [...]
Primary FSGS: Using Proteinuria as an Endpoint
Focal segmental glomerulosclerosis (FSGS) is a histologic description with numerous etiologies and proposed pathogenic mechanisms. Proteinuria, frequently associated with [...]
Reducing Kidney Function Decline
A recent Core Curriculum in AJKD from Theresa K. Chen and colleagues focuses on one of the most bread-and-butter topics for nephrology—reducing kidney function decline [...]
Management of Hyperphosphatemia in Patients With CKD Leaves Nephrologists in a Bind
One of my favorite aspects of being a nephrologist is rounding at the dialysis unit. Using a team-based approach (with the patient at the center of the team) we work [...]
The Rise of the LVAD and the Fall of the eGFR: A Commentary on LVAD Patients Receiving Maintenance Dialysis and Rivalry
The 1960s in the United States was a roller-coaster of a decade characterized by protests for the civil rights movement, the war in Vietnam, activists demanding more rights [...]
Renal Ciliopathies: A Pediatric Nephrology Perspective
The non-motile primary cilium, a specialized organelle found in nucleated mammalian cells, plays an important role in human biology due to its pleiotropic effects. This [...]
The Serendipitous Complement of IgA Nephropathy: Are We Futuristic Yet?
IgA nephropathy (IgAN) is the most common cause of primary glomerulonephritis worldwide. It is characterized by glomerular mesangial matrix expansion and mesangial cell [...]