Commentary
Commentaries are short perspectives by experts on AJKD articles or nephrology news.
Acute kidney injury (AKI) occurs frequently and is associated with increased morbidity and mortality in pediatric patients. Iodinated contrast has often been implicated as a risk factor for the development of AKI. The mechanisms of contrast-induced
[read more...]It is not a coincidence that salt makes food taste so much better and that women may crave it during pregnancy. Sodium is the core of our extracellular volume, an ultimate requirement for blood pressure and organ perfusion. Lack of sodium means lack
[read more...]Kidney disease carries a high burden for individual patients and for the medical system as a whole. End-stage kidney disease (ESKD) is associated with high mortality and decreased quality of life for many reasons including residual symptoms, pill
[read more...]‘The average Canadian is slightly less active than a (motionless) fire hydrant’ – Andrew Pipe If this statement is true for the average Canadians, one wonders if it also rings true for our neighbors to the south. Such bombastic rhetoric
[read more...]A familiar problem. A problem that sits inside an increasingly convoluted landscape of treatment options. Atrial fibrillation and advanced chronic kidney disease (CKD): Do we anticoagulate? Which agent to use? How much? We all face these questions
[read more...]Autosomal dominant tubulointerstitial kidney disease (ADTKD) was first described in 1944 and has many names – medullary cystic kidney disease type 1 and type 2 or familial juvenile hyperuricemic nephropathy type 1 and type 2. Reports in the early
[read more...]Lead as an element has a storied history beyond that of medicine – it has played a major role in the development of civilization itself. The utility of lead metal dates back thousands of years, where its use was prevalent due to the ease by which
[read more...]During NephMadness 2017, the newcomer ‘SGLT2 inhibitors’ team for the Diabetic Nephropathy region surprised the competition and made it all the way to the Filtered Four where it was knocked out by the eventual winner Genes in ESKD Disparity. In
[read more...]CRISPR (clustered regularly interspaced short palindromic repeats) gene editing is making huge waves in biomedical research. In fact, the lay press is devoting significant coverage to CRISPR as well. See this interesting piece on CRISPR from 60
[read more...]Providing kidney transplantation to HIV-positive ESKD patients was until recently considered to be a high-risk endeavour but is now almost routine. It is topical too, with the HIV Organ Policy Equity (HOPE) Act, allowing HIV+ to HIV+ transplants,
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