Commentary
Commentaries are short perspectives by experts on AJKD articles or nephrology news.
Data from epidemiological studies suggest coffee consumption may be associated with kidney (and other) outcomes, specifically a higher eGFR or less CKD. This is speculated to be due to anti-inflammatory, anti-oxidant, and anti-fibrotic effects of
[read more...]Proton pump inhibitors (PPIs) are amongst the most frequently prescribed medications with an estimated 15 million in the US taking prescription PPIs, making the estimated prevalence around 7.8% of the adult population. This number doesn’t even
[read more...]Many different definitions of contrast-induced nephropathy (CIN) have appeared in the literature since it was first reported in 1954. It is commonly defined as an acute decline in kidney function following the administration of intravenous iodinated
[read more...]Understanding the pathophysiologic mechanism(s) of thiazide-associated hyponatremia (TAH) is a coming-of-age moment for nephrologists. Sure, we all learned in medical school that thiazides can cause hyponatremia, hypercalcemia, hypokalemia, etc. but
[read more...]Tension – nephrologists live in it. The tension between trying to delay chronic kidney disease (CKD) progression whilst also preparing a patient for dialysis. Tension with administrators who are targeting metric achievement when we know that
[read more...]Acute kidney injury (AKI) is common in hospitalized patients and is associated with high morbidity and mortality, especially if requiring renal replacement therapy. Continuous renal replacement therapy (CRRT) is indicated in patients who are
[read more...]Women of reproductive age with chronic kidney disease (CKD) who desire to have children face potential complications during pregnancy. Today we will use a recent AJKD perspective, “Women’s Reproductive Health for the Nephrologist,” in addition
[read more...]Overview of Metabolic Acidosis in CKD The presence of a mildly diminished bicarbonate in advanced chronic kidney disease (CKD) is one of the more polarizing topics in nephrology. Some would argue that the impaired acid-base homeostasis will lead
[read more...]When I was a medical resident, a novel developmental therapy for the treatment of certain cancers was to medically shut off the blood supply and cause ischemia to the mass. Avastin (bevacizumab), or anti-VEGF (vascular endothelial growth factor)
[read more...]Intradialytic hypotension (IDH) is sometimes defined as a decrease in systolic BP by ≥20 mm Hg or a decrease in mean arterial pressure of 10 mm Hg associated with symptoms. There are, however, other definitions of IDH in the literature. Whereas
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