Renal Ciliopathies: A Pediatric Nephrology Perspective
The non-motile primary cilium, a specialized organelle found in nucleated mammalian cells, plays an important role in human biology due to its pleiotropic effects. This [...]
Commentary
Commentaries are short perspectives by experts on AJKD articles or nephrology news.
The Serendipitous Complement of IgA Nephropathy: Are We Futuristic Yet?
IgA nephropathy (IgAN) is the most common cause of primary glomerulonephritis worldwide. It is characterized by glomerular mesangial matrix expansion and mesangial cell [...]
NSAIDs vs OPIOIDS – ROUND 3, FIGHT!
“Four legs good, two legs bad.” – Snowball’s summary of the Seven Commandments of Animalism, Animal Farm Similar to Snowball’s cry, ‘NSAIDs bad, Opioids [...]
SGLT2 Inhibitors and AKI: Time to Ditch the Dogma
Sodium/glucose cotransporter 2 inhibitors (SGLT2i / gliflozins) are a novel class of medications which act by inhibiting the SGLT2 transporter located in the S1 segment of [...]
To Post or Not to Post: Ethics of Social Media Use in Living Donation and Kidney Transplantation
From 2015 to 2019, the United Network for Organ Sharing (UNOS) reported that only 18% of all kidney allografts were procured from living donors. Living donation is associated [...]
Association of HLA Typing With Posttransplantation Membranous Nephropathy
Membranous nephropathy (MN) is the most common cause of primary nephrotic syndrome in adults of European ancestry. A better understanding of the pathophysiology has emerged [...]
Can Histopathology Assist in Predicting the Time of Kidney Failure?! What’s New!
Predicting progression is one of the most important and challenging jobs for a nephrologist. Current estimation in clinical practice is based on demographics, clinical [...]
When the Going Gets Tough in a Pandemic…Optimizing CKRT Resources
SARS-CoV2 is a virus that has shaken the scientific community to its core. As we struggle to catch up to a rapidly evolving global pandemic, it is of utmost importance that [...]
Telemedicine in Nephrology
The COVID-19 pandemic presented unique challenges to both patients trying to obtain medical care and physicians providing the care. During this unprecedented time, [...]
Fistula Cannulation: A Hot Button Issue
That the arteriovenous fistula (AVF) is the lifeline for hemodialysis is a well-worn but well deserved cliché. The AVF has been a trusted vascular access for the last 55 [...]