AJKD Blog

IgA nephropathy (IgAN) is the most common immune-mediated glomerular disease worldwide. Advanced understanding of the role of complement in IgAN pathogenesis has motivated the development of complement inhibition as a therapeutic strategy. In a Mini-Review recently published in AJKD, authors Jia Wei Teh, Sinead Stoneman, and Michelle M. O’Shaughnessy provide an overview of the role of complement in the pathogenesis and progression of IgAN and summarize current and emerging [...]

Bertram Pitt is professor emeritus of the University of Michigan School of Medicine where he spent 15 years as the director of the Division of Cardiology. His research in practically all areas of cardiovascular disease includes special emphasis on ischemic heart disease and heart failure. Dr. Pitt is the author of almost 500 papers and chapters in books and has served on the editorial board on a number of journals in cardiovascular disease.   Michael Holinstat is a Professor of [...]

Systemic lupus erythematosus (SLE) is a chronic, multiorgan autoimmune disease, with lupus nephritis (LN) affecting up to 60% of patients. Early diagnosis and treatment are critical for preserving kidney function. In a Review recently published in AJKD, the authors discuss current and emerging therapies for proliferative and membranous LN with a focus on strategies targeting underlying mechanisms of disease in LN. AJKDBlog’s Interviews Editor, Timothy Yau chatted with authors Niraj B. Desai, [...]

SPECIAL ANNOUNCEMENT: This entire issue will be freely available until May 30, 2026 in celebration of the NKF Spring Clinical Meeting Editor’s Note: We asked authors of Original Investigations to provide short plain-language summaries that would briefly summarize what inspired their study, the basic approach taken, what was learned, and why it matters. We hope our readers will find this valuable in helping them keep up with the latest research in the field of nephrology. Highlights from [...]

The NephMadness Court of Champions is welcoming a 14th member: B-cell Modulators This year entries continued to reflect the general decline in social media popularity… … while international entries stayed pretty steady. As usual, NephMadness 2026 required the talent, effort, and time of an extensive team.  These folks make it all possible! We’d like to take this opportunity to recognize their contributions (with apologies to anyone we may have inadvertently missed): Blue [...]