Implementation of clinical genetic testing into the routine diagnostic workup of patients with kidney disorders can improve care when employed with proper patient selection. Due to advances in technology, testing with curated gene panels associated with kidney diseases are commercially available, are relatively inexpensive, and have quick turnaround time. A recently published Core Curriculum by Abraham W. Aron and Neera K. Dahl  highlights these and other topics in clinical genetic testing to enhance utilization in the general nephrology patient population.

Patient characteristics that increase the diagnostic yield of genetic testing. Identifying patients with a high pretest probability of having a genetic etiology of their kidney disorder will allow for more targeted and effective use of clinical genetic testing. Figure 1 from Aron et al , © National Kidney Foundation.

AJKDBlog’s Interviews Editor, Timothy Yau (@Maximal_Change), sat down with Dr. Anuja Java to dive into the benefits of clinical genetic testing in the nephrology patient population.

If the embedded player above doesn’t work, please click here to watch the video interview. Special thanks to Dr. Java for her time and expertise.

To view this Core Curriculum by Aron and Dahl [FREE], please visit AJKD.org:

Title: Clinical Genetic Testing in Nephrology: Core Curriculum 2024
Authors: Abraham W. Aron and Neera K. Dahl
DOI: 10.1053/j.ajkd.2024.05.011

Core Curricula aim to give trainees in nephrology a strong knowledge base in core topics in the specialty by providing an overview of the topic and citing key references, including the foundational literature that led to current clinical approaches. All Core Curricula are freely available on AJKD.org