NephMadness 2015: APOL1, The Champion
Barry I. Freedman, MD, FACP is John H. Felts, III Distinguished Professor and Chief, Section on Nephrology at Wake Forest School of Medicine. His research focuses on [...]
APOL12015
The APOL1 risk alleles, G1 and G2, are mutually exclusive (never occur on the same chromosome copy) and 2 copies are necessary to confer kidney disease risk (genotype may be G1/G1, G2/G2, or the compound heterozygous state of G1/G2). Variation in these alleles is now known to be responsible for the vast majority excess risk of non-diabetic kidney disease including FSGS, HIV-associated nephropathy, and unspecified CKD in African Americans.
NephMadness 2015 Championship Match: APOL1 in Kidney Disease – What’s the Molecular Mechanism?
David Friedman, MD, is a nephrologist at Beth Israel Deaconess Medical Center and an assistant professor at Harvard Medical School. His laboratory studies the genetics of [...]
NephMadness 2015: Introducing the Final Four!
The Final Four Sudden Cardiac Death in ESRD vs Furosemide Stress Test Winner: Sudden Cardiac Death in ESRD 4-3 split With the narrowest of margins Team Sudden Cardiac Death [...]
NephMadness 2015: The 8 Regional Winners
The Elite 8 is the final four of our tournament. In the NCAA tournament the final four represent the four regional winners. In NephMadness the Elite eight represent the 8 [...]
NephMadness 2015: Genetics • Second Round Results
Autosomal Dominant Tubulointerstitial Nephritis vs Epigenetics Winner: Autosomal Dominant Tubulointerstitial Nephritis 4-3 split UMOD & MUC1 Nephropathy were unknowns [...]
NephMadness 2015: Genetics • First Round Results
See the Current Standings! | For more on NephMadness 2015 | #NephMadness or #GeneticsRegion on Twitter AD Tubulointerstitial Nephritis vs AR Tubulointerstitial Nephritis [...]
NephMadness 2015: Bracketology from Jonathan Hogan
Last year Dr. Hogan was the selection committee member for the biologics region. This year he has analyzed the brackets and making his call for the ultimate champion. In his [...]
NephMadness 2015: Genetic Nephrology Region
Submit your picks! | For more on NephMadness 2015 | #NephMadness or #GeneticsRegion on Twitter Genetics is a disparate collection of franchise players and rising stars. Just [...]