AJKD recently published a Perspective on Mesoamerican Nephropathy (MeN) focusing on the theory of heat stress and exercise-induced uric acid crystalluria as mechanisms of injury. MeN is a chronic tubulointerstitial nephropathy with a variety of proposed mechanisms including exposure to heavy metals and pesticides, use of non-steroidal anti-inflammatory agents, and recurrent dehydration from outdoor work. The theory that uric acid–induced injury may play a role in MeN may have knock-on significance for causes of acute kidney injury and other etiologies of chronic kidney disease. Test your knowledge on this emerging story with the questions listed below.
Post prepared by Dr. Paul Phelan, AJKD Blog Contributor. For a PDF version of the questions & answers, please click here.