Phelan

Coffee Consumption and Kidney Function

June 4, 2020 // 0 Comments

Data from epidemiological studies suggest coffee consumption may be associated with kidney (and other) outcomes, specifically a higher eGFR or less CKD. This is speculated to be due to anti-inflammatory, anti-oxidant, and anti-fibrotic effects of [read more...]

Ethical Challenges of APOL1 Testing in Living Kidney Donors

August 21, 2019 // 0 Comments

The identification of APOL1-related kidney disease and recognition of its large contribution to excess risk of end-stage kidney disease (ESKD) in people of West African origin has been one of the biggest stories in nephrology over the past 2 decades [read more...]

Applying Transcriptomics to Fistula Failure – A Novel Approach

July 11, 2019 // 0 Comments

An arteriovenous fistula (AVF) is a unique vascular structure leading to distinctive endothelial insults which may contribute to non-maturation or failure of the access. Up to 50% of AVFs undergo aberrant remodeling leading to stenotic segments, [read more...]

#NephMadness 2019: Plasma Exchange Region

March 15, 2019 // 0 Comments

Submit your picks! | NephMadness 2019 | #NephMadness | #PLEXRegion Selection Committee Member: Andre Kaplan Andre Kaplan is Professor of Medicine and Chief of Blood Purification at UConn Health and is currently President-Elect of the [read more...]

The Evolution of Kidney Transplantation in HIV-Positive Patients

July 20, 2018 // 0 Comments

Providing kidney transplantation to HIV-positive ESKD patients was until recently considered to be a high-risk endeavour but is now almost routine. It is topical too, with the HIV Organ Policy Equity (HOPE) Act, allowing HIV+ to HIV+ transplants, [read more...]

Use of Omics Technologies in Nephrology

June 8, 2018 // 0 Comments

Using omics techniques to provide comprehensive molecular analysis in an unbiased fashion is a hot topic in medicine. Approaches include genomics (DNA), transcriptomics (RNA), proteomics (proteins), and metabolomics (metabolites). In a recent [read more...]

#NephMadness 2018: Transplantation Region

March 15, 2018 // 7 Comments

Submit your picks! | NephMadness 2018 | #NephMadness | #TransplantRegion Selection Committee Member for the Transplantation Region: Dorry Segev, MD Dr. Segev is the Marjory K. and Thomas Pozefsky Professor of Surgery and Epidemiology and [read more...]

HLA Epitope Matching for Mere Mortals

February 13, 2018 // 0 Comments

Human leukocyte antigen (HLA) epitope matching is something you’ve heard about but you can’t exactly remember the specifics. You might remember it as a contender in the Transplant Basic Science region of NephMadness 2016; however, you cannot [read more...]

How Did Northern Ireland Revolutionize Their Living Kidney Donor Transplantation Program?

December 20, 2017 // 0 Comments

A recent article published in AJKD by Graham and Courtney describes a quality improvement project in Belfast City Hospital to facilitate living kidney donation. Prior to 2010, this center had low rates of living kidney kidney transplantations, 4.3 [read more...]

Living Donor Transplantation in aHUS Cohort At Risk for Recurrence

September 20, 2017 // 0 Comments

Atypical hemolytic uremic syndrome (aHUS), often with pathogenic mutations in complement regulatory genes, has traditionally been associated with poor renal transplant survival due to a high risk of recurrence. The introduction of the terminal [read more...]

AJKD Blog

Official Blog of the American Journal of Kidney Diseases