Phelan

#NephMadness 2018: Transplantation Region

March 15, 2018 // 1 Comment

Submit your picks! | NephMadness 2018 | #NephMadness | #TransplantRegion Selection Committee Member for the Transplantation Region: Dorry Segev, MD Dr. Segev is the Marjory K. and Thomas Pozefsky Professor of Surgery and Epidemiology and [read more...]

HLA Epitope Matching for Mere Mortals

February 13, 2018 // 0 Comments

Human leukocyte antigen (HLA) epitope matching is something you’ve heard about but you can’t exactly remember the specifics. You might remember it as a contender in the Transplant Basic Science region of NephMadness 2016; however, you cannot [read more...]

How Did Northern Ireland Revolutionize Their Living Kidney Donor Transplantation Program?

December 20, 2017 // 0 Comments

A recent article published in AJKD by Graham and Courtney describes a quality improvement project in Belfast City Hospital to facilitate living kidney donation. Prior to 2010, this center had low rates of living kidney kidney transplantations, 4.3 [read more...]

Living Donor Transplantation in aHUS Cohort At Risk for Recurrence

September 20, 2017 // 0 Comments

Atypical hemolytic uremic syndrome (aHUS), often with pathogenic mutations in complement regulatory genes, has traditionally been associated with poor renal transplant survival due to a high risk of recurrence. The introduction of the terminal [read more...]

The Uncertainty Over Treatment Options for Uremic Pruritus

August 9, 2017 // 0 Comments

A recent article in AJKD by Simonsen et al (Open Access) describes a systematic review of treatment options for uremic pruritis, a debilitating condition in patients with end-stage renal disease (ESRD) and an identified priority for renal research [read more...]

Urgent-Start Peritoneal Dialysis and Mechanical Complications

June 15, 2017 // 1 Comment

Peritoneal dialysis (PD) is a patient-centered and cost-effective option for ESRD patients, yet only 7% of prevalent US patients are on PD. This relative underutilization may be due in part to physician preference, lack of training during [read more...]

#NephMadness 2017: History of Nephrology Region

March 7, 2017 // 0 Comments

Submit your picks! | NephMadness 2017 | #NephMadness or #HistoryRegion Selection Committee Member for the History Region: Neil Turner, MD, PhD Dr. Turner is Professor of Nephrology at the University of Edinburgh in Scotland. His research [read more...]

PPI Use & Hip Fracture in Kidney Transplantation

January 26, 2017 // 0 Comments

Patients with ESRD have a greater fracture risk than the general population. Kidney transplantation often ameliorates renal bone disease but brings additional bone risk such as corticosteroid use, and these patients are at particularly high risk of [read more...]

Rethinking Renal End Points for AKI in Clinical Trials

November 22, 2016 // 0 Comments

AKI is common, has no treatment aside from supportive care, and is associated with increased patient morbidity and mortality. This has led to renewed vigor in the search for effective therapies. However, despite many promising preclinical studies, [read more...]

Urine α1-Microglobulin as a Biomarker of Tenofovir-induced Tubular Injury

September 27, 2016 // 1 Comment

Tenofovir disoproxil fumarate (TDF) is a nucleotide analog reverse transcriptase inhibitor. It is a component of several antiretroviral regimens in the management of HIV (human immunodeficiency virus) as well as a treatment for hepatitis B. It is [read more...]

AJKD Blog

Official Blog of the American Journal of Kidney Diseases