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The Fellows-In-Training (FIT) Bowl is always one of the most engaging events for trainees at #KidneyWk. This year, there was standing room only for the finals, which pitted nephrology fellows from Mt. Sinai @ISMMSKidney against those from Mass General/Brigham @MGHKidney/@BWHKidney.

As you can see in the picture below, the matchup was incredibly close, with both teams virtually tied heading into the final jeopardy category.

Super Sinai Nephrons played conservatively, and even though they answered the question correctly, did not wager enough to edge out the #Trollvaptans from Boston.

Congratulations to @MGHKidney/@BWHKidney, as well as all the FIT Bowl participants!

And if you are a fellow in-training, consider participating in next year’s tournament!

Here below are selected questions from the preliminary, semi-final, and final round matchups so you can test your own skills:

1. This is the concentration of hydrogen ions in blood when the pH is normal (need units as well).
2. Calcineurin inhibitors prevent the nuclear translocation of this protein.
3. This channel is responsible for flow-dependent potassium secretion in the collecting duct.
4. This compound is responsible for the endemic of Balkan nephropathy.
5. This genetic disorder is characterized by early onset kidney failure, hyperuricemia, and a mutation in the gene that encodes uromodulin.
6. According to KDIGO, ESA therapy should not be used to maintain a hemoglobin level above this level.
7. Paraproteins that inhibit Factor H can sometimes cause this form of MPGN.
8. Dialysis water systems must be routinely checked for this, which is found in the outer membrane of gram negative bacteria.
9. Increased levels of this anti-angiogenic molecules have been implicated in the pathogenesis of preeclampsia.
10. This medication has been shown to reduce the risk of pre-eclampsia in high risk patients.
11. The form of monoclonal gammopathy of renal significance abbreviated PGNMID stands for this.
12. Gestational diabetes insipidus is caused by placental production of this.
13. This form of hypokalemic hypertension gets worse with spironolactone use and pregnancy.
14. Despite being autosomal dominant, it is thought that two hits are required for this mutation in this gene to result in the most common inherited cause of renal failure in adults.
15. This is the aldosterone to plasma renin activity (PRA) ratio cutoff used for the diagnosis of primary hyperaldosteronism.
16. Entresto is a combination pill for heart failure that contains this ARB.
17. A clonidine suppression test may be used in the diagnostic algorithm of this disorder.
18. Described in 1931 as a cure for hypertension, this surgical precursor to catheter-based renal denervation often resulted in debilitating side effects.
19. Medications that break disulfide bonds are used to treat this type of stone.
20. If the core of a radio-opaque stone on KUB has lower Hounsfield units on CT, the core Is likely composed of this compound.
21. A male patient with hearing loss, hematuria, elevated creatinine and a mother with hematuria likely has a mutation in this gene.
22. This is the molecular mechanism of action of belatacept.
23. In peritoneal dialysis, peritonitis is defined as a fluid leukocyte count above this level.
24. In a HD water treatment system, the water softener removes these two elements by ion exchange with sodium.
25. In 1934, this famous pathologist used dogs to develop the 2-kidney 1-clip model of renal artery stenosis.

Scroll down for answers!

1. What is 40 nmol/L?
2. What is nuclear factor of activated T-cells, or NFAT?
3. What is Maxi-K, also known as Big K or BK channel?
4. What is aristolochic acid?
5. What is autosomal dominant tubulointerstitial kidney disease (ADTKD)?
6. What is 11.5 mg/dL?
7. What is C3 glomerulopathy, or C3GN?
8. What is lipopolysaccharide (LPS) endotoxin?
9. What is soluble FLT-1?
10. What is aspirin?
11. What is proliferative glomerulonephritis with monoclonal immunoglobulin deposits?
12. What is arginine vasopresinase?
13. What is Geller’s syndrome (gain of function mutation of mineralocorticoid receptor)?
14. What is polycystin 1?
15. What is 20:1?
16. What is valsartan?
17. What is a pheochromocytoma?
18. What is sympathectomy or splanchnicectomy?
19. What are cysteine stones?
20. What is uric acid?
21. What is COL4A5?
22. What is co-stimulatory blockade?
23. What is WBC > 100?
24. What are calcium and magnesium?
25. Who is Harry Goldblatt?

– Post prepared by Timothy Yau, AJKD Social Media Editor. Follow him @Maximal_Change.

BONUS: Check out his Tweetorial on the sGLT2i educational symposia