KDIGO Anemia Guidelines: An Interview
The prevalence of anemia is high in people with chronic kidney disease (CKD) and increases as the disease advances. The Kidney Disease Outcomes Quality Initiative (KDOQI) [...]
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Chronic Kidney Disease Prevalence in Africa: An Interview
Chronic kidney disease (CKD) is a global public health concern, but its burden in Africa is poorly defined. George et al recently combined individual-level and summary data [...]
Malignancy in Kidney Transplant Recipients: An Interview
Kidney transplant recipients are at least twice as likely to develop cancer compared with immunocompetent people. Cancer is now the second leading cause of death in kidney [...]
Pentoxifylline for Diabetic Kidney Disease: An Interview
For many years, the only specific pharmacologic intervention to decrease end-stage kidney disease in diabetic kidney disease was renin-angiotensin-aldosterone system [...]
Dialysis Facility Closure Trends Over the Past Decade: An Interview
Between 2006 and 2016, the number of US dialysis facilities experienced steady annual growth. Recent data suggest a reversal in this trend. Varkila et al examined trends in [...]
B-Cell Modulators in IgA Nephropathy: An Interview
In IgA nephropathy (IgAN), elevated levels of the circulating autoantigen galactose-deficient IgA1 are critical to disease pathogenesis. Genetic as well as in vitro, in vivo, [...]
Response to Rituximab as a Maintenance Therapy in Adult INS: An Interview
Rituximab effectively limits the number of relapses in childhood idiopathic nephrotic syndromes (INS) and reduces exposure to corticosteroids and other immunosuppressants. [...]
Apixaban for Atrial Fibrillation in Dialysis: An Interview
Atrial fibrillation is common among patients with kidney failure treated with hemodialysis. A recent study published in AJKD by Winkelmayer et al examined the efficacy and [...]
Real-World Evidence for GLP-1 Receptor Agonists Across the CKD Spectrum
Dr. Linda-Marie Lavenburg is an Assistant Professor of Medicine at the University of Pittsburgh Renal-Electrolyte Division. She is an internal-medicine and pediatric-trained [...]
Complement Inhibition in IgAN: An Interview
IgA nephropathy (IgAN) is the most common immune-mediated glomerular disease worldwide. Advanced understanding of the role of complement in IgAN pathogenesis has motivated [...]