A recent Core Curriculum in AJKD from Theresa K. Chen and colleagues focuses on one of the most bread-and-butter topics for nephrology—reducing kidney function decline in patients with chronic kidney disease (CKD). This paper provides a comprehensive review of various clinical trials as they apply to everyday clinical nephrology practice. It focuses on various opportunities that allow for slowing the progression of CKD. A graphical abstract and summary of tables for the paper are outlined in this piece.
Blood Pressure control:
SGLT2 inhibitors and GLP1-receptor agonists:
Chronic metabolic acidosis and dietary protein restriction:
Title: Reducing Kidney Function Decline in Patients With CKD: Core Curriculum 2021
Authors: Teresa K. Chen, Christopher J. Sperati, Sumeska Thavarajah, and Morgan E. Grams
Articles in the Core Curriculum aim to give trainees in nephrology a strong knowledge base in core topics in the specialty by providing an overview of the topic and citing key references, including the foundational literature that led to current clinical approaches.