Nephrolithiasis: An Interview

Kidney stone disease, also known as nephrolithiasis or urolithiasis, is a disorder in which urinary solutes precipitate to form aggregates of crystalline material in the urinary space. The incidence of nephrolithiasis has been increasing, and the demographics have been evolving. In a Core Curriculum recently published in AJKD, Shani Shastri and colleagues provided a case-based overview of nephrolithiasis, divided by the individual stone types.

AJKDBlog’s Interviews Editor, Timothy Yau @Maximal_Change, recently sat down to discuss all things kidney stone with his colleagues, Anna Zisman @anna_zisman and Bill Whittier @TWhittier_RUSH.

If the embedded player above doesn’t work, please click here to watch the video interview. Special thanks to Drs Zisman and Whittier for their time and thoughts!

Overview of the pathogenesis of nephrolithiasis. Figure 1 from Shastri et al, AJKD.

To view this Core Curriculum (FREE), please visit

Title: Kidney Stone Pathophysiology, Evaluation and Management: Core Curriculum 2023
Author: Shani Shastri, Jiten Patel, Kamalanathan K. Sambandam, Eleanor D. Lederer
DOI: 10.1053/j.ajkd.2023.03.017

Core Curricula aim to give trainees in nephrology a strong knowledge base in core topics in the specialty by providing an overview of the topic and citing key references, including the foundational literature that led to current clinical approaches. All Core Curricula are freely available on

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