onco-nephrology

The Expanding Role of Proteasome Inhibitors in Treatment of Renal Diseases

April 14, 2014 // 2 Comments

Invited commentary by Dr. Parmjeet Randhawa Bortezomib is a proteasome inhibitor initially licensed for use in patients with refractory multiple myeloma. More recently, [...]

Another Look at Eculizumab for Atypical Hemolytic Uremic Syndrome

December 19, 2013 // 0 Comments

Atypical hemolytic uremic syndrome (aHUS) is a severe form of thrombotic microangiopathy that frequently causes acute kidney injury (AKI) and leads to chronic kidney disease [...]

Reduced Kidney Function and Cancer Death: Is There an Increased Risk?

October 31, 2013 // 0 Comments

It is well known that chronic kidney disease (CKD) is linked to a higher cardiovascular mortality and increased risk of malignancy. What is unclear is whether reduced kidney [...]

Cancer-Associated Type B Lactic Acidosis

September 12, 2013 // 0 Comments

Lactic acidosis is an acid-base disturbance commonly seen in hospitalized patients. Most cases of lactic acidosis are due to hypoperfusion (type A lactic acidosis), which [...]

What Is the Evidence for Rasburicase in Tumor Lysis Syndrome?

July 11, 2013 // 0 Comments

Tumor lysis syndrome (TLS) is not uncommon on the oncology ward. A novel agent, rasburicase, has been used to treat the uric acid nephropathy with some success. A recent [...]

Nephrectomy and CKD

May 30, 2013 // 1 Comment

In the recent study, “Patient and Caregiver Knowledge and Utilization of Partial Versus Radical Nephrectomy: Results of a National Kidney Foundation Survey to Assess [...]

Hematopoietic Stem Cell Transplantation–Related Kidney Injury

February 19, 2013 // 0 Comments

Hematopoietic stem cell transplantation (HSCT) exposes the kidney to a multitude of injuries, including acute kidney injury (AKI), hypertension, glomerular disease, and [...]