Recap of eAJKD’s coverage of the ASN’s Kidney Week 2012

Check out all of eAJKD’s coverage of the American Society of Nephrology’s Kidney Week 2012 below and @eAJKD on Twitter! Drs. Kenar Jhaveri, Matt Sparks, Joel Topf, and Magdalena Madero from the eAJKD team covered Kidney Week for the blog. eAJKD’s Drs. Kellie Calderon and Vinay Nair helped edit meeting posts. Career Choices in Nephrology […]

Kidney Week 2012: AKI in the Bone Marrow Transplant Unit

Lecture: Ward Rounds and Acute Kidney Injury Dr. Sarah Faubel created this 2-hour lecture block. The idea was to look at four different theater of operations and look do a deep dive on how the causes and treatments of acute kidney injury differ. This is a salute to Bayesian logic and attempts to give doctors […]

Kidney Week 2012: Drug-induced Acute Interstitial Nephritis

Manuel Praga, MD Madrid Spain Drug-induced AIN In the elderly, the incidence of AIN has increased over the last 10 years. True incidence might be higher as biopsies usually are not performed in elderly patients, and milder forms of AKI typically are not detected. Urine sediment can be used to evaluate drug-induced AIN (leukocyturia in […]

Kidney Week 2012: Novel Agents Causing Nephrotoxicities

Mark Perazella, MD Yale University Proximal Tubular Damage Tenofovir: protienuria and rapid decline of kidney function (VHA database). Elvitegravir, cobicistat, emtricitabine, tenofovir disoproxil fumarate: (new HIV drug): Once daily dose. Two phase 3 trials showed that adverse renal effects were higher than other tenofovir -containing drugs, and Fanconi syndrome and AKI were described. Animal studies […]

Kidney Week 2012: Late Breaking Trials: ANCA Vasculitis New Trial

Mycophenolate versus cyclophosphamide for induction of ANCA-associated vasculitis.  The lead author and presenter is Dr. Rachel B. Jones. The current standard of care is cyclophosphamide and glucocorticoids for induction of ANCA-associated vasculitis. Cyclophosphamide has numerous toxicities including malignancy, infertility, and infection. Mycophenolate mofetil (MMF) is an oral drug with significant GI side effects but an […]

Kidney Week 2012: Acute Kidney Injury in the Neuro ICU

Dr. Sarah Faubel created this 2-hour lecture block. The idea was to look at four different theater of operations and look do a deep dive on how the causes and treatments of acute kidney injury differ. This is a salute to Bayesian logic and attempts to give doctors a refined view of pre-test probabilities for […]

Kidney Week 2012: Late Breaking Trials: EVOLVE

The cinacalcet randomized controlled trial: EVOLVE. Speaking is the lead author Glen Chertow. Disclosure: I (Joel Topf) was a primary investigator for EVOLVE. The second trial to be presented at late breaking and high-impact trials is EVOLVE. Largest dialysis study Longest dialysis study Most international dialysis study Only double-blind dialysis study If you complain that […]

Kidney Week 2012: Late Breaking Trials: TEMPO

We now have an effective medication for autosomal dominant polycystic kidney disease. Tolvaptan, the oral vaptan approved for hyponatremia, was effective at slowing cyst growth and loss of GFR in the TEMPO 3:4 trial. TEMPO stands for Tolvaptan Efficacy and safety in Management of Polycystic kidney disease and its Outcomes. The data was presented by […]

Kidney Week 2012: Direct Renin Inhibition in Non-diabetic Kidney Disease (DRINK study)

An interim analysis from the DRINK trial was presented as an oral communication by Tang et al on Friday Nov 2nd. Seventy six non-diabetic patients with CKD stages 3-4 were randomized to receive either aliskiren or placebo in addition to a maximal dose of angiotensin receptor blockade (ARB). Primary outcome was CKD progression, ESRD or […]

Kidney Week 2012: AKI in the Trauma ICU

Lecture: Ward Rounds and Acute Kidney Injury Dr. Sarah Faubel created this 2-hour lecture block. The idea was to look at 4 different theater of operations and do a deep dive on how the causes and treatments of acute kidney injury differ. This is a salute to Bayesian logic and attempts to give doctors a […]

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