2019

Metabolic Acidosis in CKD

October 21, 2019 // 0 Comments

Overview of Metabolic Acidosis in CKD The presence of a mildly diminished bicarbonate in advanced chronic kidney disease (CKD) is one of the more polarizing topics in nephrology. Some would argue that the impaired acid-base homeostasis will lead [read more...]

Test Your Knowledge: Complement

October 18, 2019 // 0 Comments

We’ve been releasing quiz questions from NephMadness 2019 every week as we count down to the NephMadness 2020 logo reveal at Kidney Week. Did you miss any of the previous quizzes? Catch up here. This week we focus on the Complement Region. The [read more...]

Can Checkpoint Inhibitors Pave the Way for A Generation of Targeted Therapies for Autoimmune Diseases?

October 15, 2019 // 2 Comments

When I was a medical resident, a novel developmental therapy for the treatment of certain cancers was to medically shut off the blood supply and cause ischemia to the mass. Avastin (bevacizumab), or anti-VEGF (vascular endothelial growth factor) [read more...]

Test Your Knowledge: Volume Assessment

October 11, 2019 // 0 Comments

NephMadness 2019 featured the Volume Assessment region. What is the best way to objectively assess the volume status of patients with end-stage kidney disease (ESKD), and on what volume-related endpoints should we base our fluid management [read more...]

Utility of Hypertonic Mannitol for the Prevention of Intradialytic Hypotension (IDH)

October 7, 2019 // 0 Comments

Intradialytic hypotension (IDH) is sometimes defined as a decrease in systolic BP by ≥20 mm Hg or a decrease in mean arterial pressure of 10 mm Hg associated with symptoms. There are, however, other definitions of IDH in the literature. Whereas [read more...]

Test Your Knowledge: Hepatorenal Syndrome

October 4, 2019 // 0 Comments

NephMadness 2019 featured the Hepatorenal Region. Patients with liver failure are sick. Patients with acute kidney injury (AKI) are sick. Put the two together and you have a fine mess. Test your knowledge on hepatorenal syndrome with the quiz* [read more...]

Highlights from the October 2019 Issue

October 1, 2019 // 0 Comments

Editor’s Note: We asked authors of Original Investigations to provide short plain-language summaries that would briefly summarize what inspired their study, the basic approach taken, what was learned, and why it matters. We hope our readers [read more...]

Test Your Knowledge: Pain

September 26, 2019 // 1 Comment

We are releasing a quiz* each week from the eight regions of NephMadness 2019, in anticipation of the NephMadness 2020 logo reveal at Kidney Week. We focused on Plasma Exchange last week and now turn to the Pain Region. Whenever we consider giving [read more...]

Cast Morphology As A Clue to the Cause of Acute Tubular Injury

September 23, 2019 // 1 Comment

PathPointers highlight important everyday teaching points when reviewing kidney histology. These brief and easy-to-read blog posts include real clinical images to demonstrate various biopsy findings. A 30-year-old man who died of a head injury was [read more...]

Test Your Knowledge: Plasma Exchange

September 19, 2019 // 0 Comments

We cannot wait to share the NephMadness 2020 logo at Kidney Week. Until then, we are releasing a quiz* each week from the eight regions of NephMadness 2019, starting with the Plasma Exchange region this week. Plasmapheresis, simply removal of [read more...]

AJKD Blog

Official Blog of the American Journal of Kidney Diseases