In CKD, the More Acid You Eat, the More Phosphorus You Excrete
In a recent AJKD article, Khairallah et al presented a prospective cohort of 980 patients with CKD enrolled in CRIC and demonstrated that higher acid load and acidosis was [...]
acid base
How Accurate Are the Formulas for the Osmolal Gap?
The osmolal gap is most commonly used in screening for toxic alcohol ingestion. In the absence of other unmeasured solutes, sodium, glucose, and urea are the primary solutes [...]
Test Your Knowledge: Assessing Acid-Base Status
A recent AJKD Teaching Case by Adrogué & Madias contrasts the physiologic and physicochemical approaches to assessing acid-base status. Test your knowledge on this topic [...]
The Many Gaps of Methanol Poisoning
In a recent AJKD article, Kraut reviews some of the pearls and pitfalls in the diagnosis and management of methanol intoxication. The clinical manifestations of methanol [...]
An Unexpected Gap: Effects of Salicylates and Other Conditions on the Serum Anion Gap
In an article recently published in AJKD, Dr. Michael Emmett reported a case of salicylate poisoning in association with a negative serum anion gap. Salicylate poisoning is [...]
Crossword: Acid-Base Basics
Given the acid-base theme this month in AJKD, this is an acid-base crossword on basic physiology. Fill the crossword out online at [...]
Test Your Knowledge: Anion Gap in Metabolic Acidosis
The serum anion gap is a common tool used in clinical practice. Recent advances have led to a new mnemonic GOLD MARK to differentiate the various causes of anion gap [...]
Test Your Knowledge: Acid-Base Disturbances in the Hemodialysis Patient
Abnormal bicarbonate levels in end-stage-renal disease (ESRD) patients are a treatment challenge. How and when to intervene has little or no evidence. In a recent article in [...]
Cancer-Associated Type B Lactic Acidosis
Lactic acidosis is an acid-base disturbance commonly seen in hospitalized patients. Most cases of lactic acidosis are due to hypoperfusion (type A lactic acidosis), which [...]
Metabolic Alkalosis: What Is the Cause?
In the April issue of the American Journal of Kidney Diseases, Yi et al present an interesting teaching case of metabolic alkalosis from an unsuspected ingestion. A [...]