#NephMadness 2021: The Filtered Four

The Championship Matchup is nearing! How are the Blue Ribbon Panel doing? How is your Bracket doing? Do you agree or disagree with the votes so far? Tweet your reaction and score with the hashtags: #Filtered4 #NephMadness


Liquid Biopsy Region vs Animal House Region

Hopping Mouse seemed to have lost the bounce in their step during this game. Microscopy Techniques came up with the easy win. 

Microscopy Techniques wins 6-3

Comments from the BRP:

Despite the intellectual stimulation of the mechanisms of urinary concentration; looking at the urine will win out in care of patients.

Sure microscopy is good and all but the ability to produce solid pee is incredible.

Let’s get the fellows re-engaged in by the bedside diagnosis. The animal model is very cool however.

What can I say? I am a visual learner. And microscopy literally changes my plans many times on rounds.


COVID-19 Region vs ICU Nephrology Region

The second game of the Effluent 8 was a close, hard fought matchup. COVID-19 in Dialysis and Dialysis Timing in Surgical ICU proved why they were both their individual region’s champions. This game was neck and neck but a mid court steal leading to a slam dunk led to victory for Dialysis Timing in Surgical ICU.

Dialysis Timing in Surgical ICU wins 5-4

Comments from the BRP:

While the impact of COVID-19 on the delivery of dialysis is high and may change some paradigms of infection prevention, after universal vaccination COVID-19 will hopefully fade as a distant nightmare, but the question of when to start kidney replacement therapy in AKI will remain.

The aftermath of the COVID pandemic will define the next decade for nephrology in countries with high rates of infection. Let’s take what we’ve learned from dialyzing these patients and improve outcomes for all with AKI.

The SICU will always be here and definitely time consuming; COVID may disappear one day?

COVID-19 will not be with us forever.

“This is such a hard one. I’m no surgeon–but KRT is a big deal. And when to do it is a big deal, too. Besides, what if someone asks me what to do on med consults during Kidney Week when all of the nephrologists are out of pocket?”


Workforce Region vs Anemia Region

Team Medical Student Interest continues their Cinderella run with a blow out win over fan favorites HIF Stabilizers. Unclear if HIF stabilizers even took the court. 

Medical Student Interest wins 8-1

Comments from the BRP:

A hard-fought game, but increasing interest in nephrology for the next generation wins out over the shiny new drug for the treatment of anemia (and how much will the HIF inhibitors cost, anyway?).

Without a workforce it will be hard to improve anyone’s anaemia.

Workforce is so important right now.

I hate being anemic (on rare occasions), but we need those Medical Students forever.

“There is nothing more stabilizing than a solid pipeline of future nephrologists. Period.”


Primary Care Region vs Artificial Kidney Region

For those looking for a close, hard fought game, this game did not disappoint. CKD Primary Care hit a huge 3 pointer to tie the game up with 1 second to go in regulation forcing the game into overtime. However, it was Implantable Bioartificial Kidney that came up with the clutch jump shot from the corner to go up by 1 with time expiring.

Implantable Bioartificial Kidney wins 5-4

Comments from the BRP:

Improved care of patients with CKD (or at risk for CKD) by PCPs has the potential to slow progression of kidney disease and may obviate the need for a bioartificial implantable kidney.

“Although CKD in primary care is likely to improve outcomes for more patients over the next decade than an implantable bioartificial kidney, I can’t get beyond hope. An implantable bioartificial kidney would revolutionise management of kidney disease for children.”

“Hmmm, based on the remaining choices I did not totally crash and burn. The Artificial Kidney is a total game changer and is the future of Nephrology. We may NEVER get the PCPs to make early diagnosis of CKD.”

“Help me help you. Literally. CKD in Primary Care for the win.

Current Standings | Match Results | Saturated 16 | Effluent 8 

 #NephMadness | @NephMadness | #Filtered4

How to Claim CME and MOC
US-based physicians can earn 1.0 CME credit and 1.0 MOC point for reading this region.

  1. Register/log in to the NKF’s Professional Education Resource Center (PERC). If you select “Physician” in the drop-down menu during registration, the ABIM ID will pop up – make sure to complete this during registration to receive MOC points after course completion.
  2. Review the activity, disclosure, and accreditation information.
  3. Click “Continue” and review Course Instructions.
  4. Complete Post-Test. Please note: By selecting “Yes” to the participation questions for each region, the corresponding Post-Test questions will appear. Click “Save Draft” to save your responses and finish later. When you are ready to submit your answers, click “Preview” to review all responses, then click “Submit.”
  5. Click “Next” to complete the Evaluation form, then click“Submit.”
  6. Claim 1.0 CME credit and 1.0 MOC point per region (up to 8.0 total for 8 regions of NephMadness).
  7. Save/print your certificate.

The CME and MOC activity will expire on June 14th, 2021.


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  1. #NephMadness 2021 Champion: Implantable Bioartificial Kidney – AJKD Blog

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