glomerular diseases

#NephMadness 2018: Pediatric Nephrology Region

March 15, 2018 // 3 Comments

Submit your picks! | NephMadness 2018 | #NephMadness | #PedsRegion “For in every adult there dwells the child that was, and in every child there lies the adult that will be.” -John Connolly, The Book of Lost Things NephMadness is pleased to [read more...]

Membranous Nephropathy in 2016: Or Should We Call It PLA2R-Related Nephropathy?

August 16, 2016 // 1 Comment

David J. Salant, MD (DS), was the Donald W. Seldin Distinguished Award recipient at the 2015 National Kidney Foundation Spring Clinical Meetings. This award was established to recognize excellence in clinical nephrology in the tradition of one of [read more...]

C4 Glomerulopathy: Should We Accept it As a New Disease?

February 29, 2016 // 0 Comments

A recent article published by AJKD reports 3 patients with nephrotic syndrome, two of whom also had hematuria. Kidney biopsy revealed mesangioproliferative glomerulonephritis in one case, membranoproliferative glomerulonephritis in the second [read more...]

Transplacental Transmission of Autoimmune Glomerular Disease

February 11, 2016 // 0 Comments

In a recent article in AJKD, Al-Rabadi et al present a case of a pregnancy patient with active membranous nephropathy (MN) and circulating autoantibodies to PLA2R, the major autoantigen in primary MN. Despite the presence of low titer circulating [read more...]

Renal Amyloidosis – What We Need to Consider, Practical Tips

January 21, 2016 // 2 Comments

The AJKD Atlas of Renal Pathology II has recently provided a succinct summary of the diagnosis of AL (light chain) amyloidosis, the most common type of renal amyloidosis, and compared it with hereditary and other non-AL amyloidosis. Related [read more...]

What Is Crescentic Glomerulonephritis?

January 14, 2016 // 0 Comments

Glomerular crescents are dramatic lesions. That, together with their often rapid and devastating clinical presentation, help to account for the prominent attention they receive. Trainees have their “differential diagnosis,” as defined by the [read more...]

ANCA Disease: How Do Patients Do on RRT?

July 16, 2015 // 2 Comments

ANCA-associated vasculitides (AAV) are among the diseases with highest morbidity and mortality encountered in clinical nephrology. Fortunately, these diseases tend to be infrequent, but represent the most common causes of rapidly progressive [read more...]

Glomerular Diseases and Complement Activation

July 2, 2015 // 0 Comments

A recent Core Curriculum by Noris and Remuzzi is on the timely topic of activation of the complement system in glomerular disease. This focuses on our evolving understanding of atypical hemolytic uremic syndrome (aHUS), membranoproliferative [read more...]

The Multifaceted Relationship Between Infection and Glomerulonephritis

June 11, 2015 // 1 Comment

In a recent article published in AJKD, Glassock et al argue that the term post-infectious glomerulonephritis not be used indiscriminately for all cases where there is a clinical history of both an infection and glomerulonephritis. It is suggested [read more...]

Test Your Knowledge: Lupus Nephritis & Thrombotic Microangiopathy

January 12, 2015 // 1 Comment

In the January issue of AJKD, El-Husseini et al describe a case of lupus nephritis-associated thrombotic microangiopathy (TMA) that was successfully treated with eculizumab, a complement inhibitor. The following questions will test your knowledge on [read more...]

AJKD Blog

Official Blog of the American Journal of Kidney Diseases