#PathPointer: Tram-Tracking in a Transplant
The aesthetic qualities of a good Jones silver stain are underrated. The black linear pattern contrasting against the colors of the counterstained tissue evokes the lead [...]
TMA
Thrombotic Microangiopathies and Stem Cell Transplant
A recent narrative review published in AJKD discusses the association between thrombotic microangiopathy (TMA) and hematopoietic stem cell transplantation (HSCT). AJKD Social [...]
I’ll Have A Gin and Tonic; Hold the Tonic
The gin and tonic is a classic cocktail, perfect with a sliver of lime on a hot summer day. But this simple-to-make drink also has a long-storied medical history that is [...]
Thrombotic Microangiopathy in Cancer Patients
Thrombotic microangiopathy (TMA) describes a set of disorders that are characterized by microvascular thrombosis, microangiopathic hemolytic anemia, thrombocytopenia, and [...]
SCM15: C4 Dense deposit Disease with TMA
Dr. Arshad Ali (AA), from Emory University School of Medicine in Atlanta, Georgia, discusses his abstract for the National Kidney Foundation’s 2015 Spring Clinical Meetings [...]
Test Your Knowledge: Lupus Nephritis & Thrombotic Microangiopathy
In the January issue of AJKD, El-Husseini et al describe a case of lupus nephritis-associated thrombotic microangiopathy (TMA) that was successfully treated with eculizumab, [...]
Eculizumab Can Be Discontinued in Selected Patients with aHUS
Since 2009, eculizumab has been successfully used for treatment of aHUS. What happens after discontinuation is less clear. Does the disease relapse? In a recent AJKD article, [...]
Factor H Deficiency and Atypical HUS
Atypical hemolytic uremic syndrome (aHUS) is characterized by excessive microvascular complement activation. Many mutations have now been described that lead to aHUS and its [...]
Hematopoietic Stem Cell Transplantation–Related Kidney Injury
Hematopoietic stem cell transplantation (HSCT) exposes the kidney to a multitude of injuries, including acute kidney injury (AKI), hypertension, glomerular disease, and [...]