TMA

Thrombotic Microangiopathy and Monoclonal Immunoglobulins: Further Evidence Supporting an Association

November 23, 2022 // 0 Comments

Miroslav Sekulic Dr. Miroslav Sekulic is a renal pathologist at Columbia University Medical Center. He has had the pleasure of training and working alongside his two fellow [...]

#PathPointer: Tram-Tracking in a Transplant

January 30, 2019 // 0 Comments

The aesthetic qualities of a good Jones silver stain are underrated. The black linear pattern contrasting against the colors of the counterstained tissue evokes the lead [...]

Thrombotic Microangiopathies and Stem Cell Transplant

October 17, 2018 // 0 Comments

A recent narrative review published in AJKD discusses the association between thrombotic microangiopathy (TMA) and hematopoietic stem cell transplantation (HSCT). AJKD Social [...]

I’ll Have A Gin and Tonic; Hold the Tonic

October 31, 2017 // 5 Comments

The gin and tonic is a classic cocktail, perfect with a sliver of lime on a hot summer day. But this simple-to-make drink also has a long-storied medical history that is [...]

Thrombotic Microangiopathy in Cancer Patients

July 6, 2015 // 2 Comments

Thrombotic microangiopathy (TMA) describes a set of disorders that are characterized by microvascular thrombosis, microangiopathic hemolytic anemia, thrombocytopenia, and [...]

SCM15: C4 Dense deposit Disease with TMA

March 26, 2015 // 2 Comments

Dr. Arshad Ali (AA), from Emory University School of Medicine in Atlanta, Georgia, discusses his abstract for the National Kidney Foundation’s 2015 Spring Clinical Meetings [...]

Test Your Knowledge: Lupus Nephritis & Thrombotic Microangiopathy

January 12, 2015 // 1 Comment

In the January issue of AJKD, El-Husseini et al describe a case of lupus nephritis-associated thrombotic microangiopathy (TMA) that was successfully treated with eculizumab, [...]

Eculizumab Can Be Discontinued in Selected Patients with aHUS

May 5, 2014 // 1 Comment

Since 2009, eculizumab has been successfully used for treatment of aHUS. What happens after discontinuation is less clear. Does the disease relapse? In a recent AJKD article, [...]

Factor H Deficiency and Atypical HUS

September 19, 2013 // 0 Comments

Atypical hemolytic uremic syndrome (aHUS) is characterized by excessive microvascular complement activation. Many mutations have now been described that lead to aHUS and its [...]

Hematopoietic Stem Cell Transplantation–Related Kidney Injury

February 19, 2013 // 0 Comments

Hematopoietic stem cell transplantation (HSCT) exposes the kidney to a multitude of injuries, including acute kidney injury (AKI), hypertension, glomerular disease, and [...]