C4 Nephritic Factor? I Still Don’t Understand C3 Glomerulopathy!
The complement system lies at the interface of innate and adaptive immunity. Perhaps its most remarkable feature is that it reacts in seconds to opsonize and/or lyse a [...]
Commentary
Commentaries are short perspectives by experts on AJKD articles or nephrology news.
#RenalDietChallenge: How Much Phosphorus Is In This Meal?
In May 2017, a group of eight nephrology healthcare workers participated in the renal diet challenge where, for three days, they followed the diet that is recommended to [...]
The Continued Importance of Qualitative Research in Kidney Disease
Qualitative data has been increasingly used to help illustrate the illness experiences of patients with dialysis-dependent kidney disease. Examples include studies detailing [...]
Uric Acid: Bedside to Bench and Back Again
For a long time, uric acid has been known as a presumably inert by-product of purine metabolism that is associated with gout and kidney stones. In recent years, there has [...]
Living Donor Transplantation in aHUS Cohort At Risk for Recurrence
Atypical hemolytic uremic syndrome (aHUS), often with pathogenic mutations in complement regulatory genes, has traditionally been associated with poor renal transplant [...]
Endovascular AVF Creation – A NEAT Option
Hemodialysis vascular access remains a major challenge for the nephrology community. While the benefits of an arteriovenous fistula (AVF) with regards to morbidity and [...]
In CKD, the More Acid You Eat, the More Phosphorus You Excrete
In a recent AJKD article, Khairallah et al presented a prospective cohort of 980 patients with CKD enrolled in CRIC and demonstrated that higher acid load and acidosis was [...]
How Accurate Are the Formulas for the Osmolal Gap?
The osmolal gap is most commonly used in screening for toxic alcohol ingestion. In the absence of other unmeasured solutes, sodium, glucose, and urea are the primary solutes [...]
The Future of Hepatitis C and Kidney Transplantation
This is Part 2 of a 2-part series on Hepatitis C and kidney transplantation. Part 1 reviewed the history of HCV, the era of IFN therapy, and the use of DAAs in patients with [...]
Hepatitis C and Kidney Transplantation: Past, Present, and Future
This is Part 1 of a 2-part series on Hepatitis C and kidney transplantation, highlighting some of the exciting breakthroughs impacting this field that have come about as a [...]